KREAMedical Aesthetics
Marylebone · Saturdays only
Polynucleotides · Marylebone, London
For the tiredness that sleep does not fix.
Polynucleotides support your skin’s own repair. Over a course of three sessions, skin can look firmer, brighter and more rested, including the delicate eye area that concealer only hides. No volume, no frozen look. You, on your best day, more often.
- 30-minute consultation with Kremena
- Eye area from £320
- Saturdays, near Baker Street
Consultation £50, redeemed against your first treatment within 90 days.
As featured in Elysium Lifestyle Magazine · Advanced Nurse Practitioner · Fully insured · Creator of The Safety Shield®
You know the look
You sleep. You drink the water. Your skin still says you had a hard week.
Somewhere in your late thirties, skin starts to slow its own repair. It holds less water, loses firmness, and the under-eyes usually go first: thinner, darker, more crepey, however early you went to bed.
Eye cream sits on top of that. Concealer covers it until 3pm. Neither one asks your skin to do anything differently.
Polynucleotides do.
What polynucleotides do
A regenerative treatment, not a cover-up.
Polynucleotides are a regenerative treatment placed just under the surface of the skin, where they support its natural repair processes. Over a course of three sessions, skin quality can improve from within: hydration, firmness, texture, and the rested look that make-up was faking.
Under-eyes that can look brighter and less tired
Fine lines and crepey texture that can look softer
Firmness and bounce through the face, neck and décolletage
Results that build gradually and look like you, not like a procedure
What to expect
Under an hour in the chair. Back to your Saturday. Repeat twice.
Treatment time
30 to 60 minutes, depending on the area
Course
3 sessions, 2 to 4 weeks apart
Downtime
Small raised areas settle within 24 to 48 hours
Results
Build gradually over the course of treatment
Consultation £50, redeemed against your first treatment within 90 days.
Meet Kremena
Ten years in clinical medicine. Now one client at a time.
Kremena Payova is an Advanced Nurse Practitioner and Independent Prescriber who spent more than a decade in clinical medicine, from emergency care to general practice, before founding KREA. She created The Safety Shield®, a registered clinical governance and patient safety framework, and she will tell you honestly if polynucleotides are not right for you. You see her at every appointment, from consultation to review.
“I treat every face the way I would want my own treated: carefully, honestly, and never too much.”
As featured in Elysium Lifestyle Magazine, May 2026
Choose your area
Start where it shows most.
Many women start with the eye area, because that is where tiredness shows first. Your exact plan is agreed with Kremena at your consultation.
Start here
Eye area
Dark, tired-looking, crepey under-eyes. Around 45 minutes a session.
£320 a session
Course of three £850
The classic
Face, neck and décolletage
Skin quality, firmness and glow across the whole area. 30 to 45 minutes.
£360 a session
Course of two £680 · Course of three £1,050
The full reset
Face and eyes
Both in one sitting, around 60 minutes. Also available as The KREA Eye Renewal programme.
£620 a session
Course of three £1,720
Consultation £50, redeemed against your first treatment within 90 days. Spread the cost with Klarna or Clearpay, subject to approval by the provider. UK residents, 18+.
Why now
Results build over weeks, not days. Start now and they arrive in time for December.
Three sessions a few weeks apart, with improvement that builds through the course. Begin in October and your skin has done its work before the invitations arrive.
Before you book
Straight answers.
What does the consultation cost?
£50 for thirty unhurried minutes with Kremena. The fee is redeemed against your first treatment if it takes place within 90 days.
Is this the same as filler?
No. Filler adds volume and changes contour. Polynucleotides work on skin quality: hydration, firmness and texture. The shape of your face stays the same.
Does it hurt?
A fine needle and a number of small points. Most people find it very tolerable, including around the eyes.
When will I see results?
They build gradually over the course of treatment. For the eye area, most of the change shows over 6 to 8 weeks, and it depends on your skin. Kremena will tell you what to expect for yours.
What if Kremena says I don’t need it?
Then you leave with honest advice and a clear picture of your skin. Saying no is part of the service.
Can I pay in instalments?
Yes. Pay in full by card or bank transfer, or spread the cost with Klarna or Clearpay, subject to approval by the provider. UK residents, 18+.
Saturdays only · by appointment
Your skin, doing what it used to do.
A consultation with Kremena, one client at a time. The £50 fee is redeemed against your first treatment within 90 days.
Practising at Charterhouse Clinic London, 98 Crawford Street, Marylebone, London W1H 2HL · a short walk from Baker Street
KREA Medical Aesthetics is an independent practice and is not part of Charterhouse Clinic London.
Every treatment is personally planned and delivered by Kremena Payova, Advanced Nurse Practitioner and Independent Prescriber. Fully insured. Adults 18+ only. Complaints: hello@kreamedicalaesthetics.co.uk